Conservation and restoration of intact sagebrush communities is a high priority given the dramatic increase recent landscape-level wildfires and the increase in invasive species.  Collaboration to restore sagebrush steppe is often implemented at the local level requiring diverse partnerships to fund and implement treatments.  This presentation focuses on collaboration between the scientific and management communities to develop a landscape context to prioritize and select restoration treatments that maximize the “footprint” of a project.  The Owyhee Uplands Pilot Project was initiated by the Bureau of Land Management’s (BLM) National Office as a pilot for implementing an “Assessment, Inventory, and Monitoring Strategy” at a regional scale.  The Owhyee Uplands is 10 million acres of a relatively intact sagebrush steppe ecosystem in the three-corners areas of Oregon, Nevada, and Idaho.  Local BLM managers requested this pilot project to describe potential and current vegetation, identify threats (primarily wildfires, invasive plants, and human disturbance) to landscape integrity, and describe treatments implemented to reduce threats.  Collaborators in the scientific community were selected to address western juniper encroachment (Juniperus occidentalis), cheatgrass extent, and to produce a current vegetation map with plant potential.  Cooperators included The Nature Conservancy, Pacific Northwest Regional Callaboratory, USDA Agricultural Research Service in Boise, Idaho and Las Cruces, New Mexico, Nevada Natural Heritage Program in Reno, Nevada, Boise State University, and personnel from the three BLM states and seven Field Offices involved in the project.   The information from the Owyhee Uplands Pilot Project was used in 2007 to help prioritize projects submitted for consideration under the Department of Interior’s 2008 Healthy Lands Initiative.  A successful partnership between science and management was the key to the implementation of a regional assessment, inventory and monitoring program.